RENAL CELL CARCINOMA BONE METASTASES: CLINICAL ADVANCES

Renal cell carcinoma bone metastases: clinical advances

Bone is a common site of metastatic spread in patients with advanced renal cell carcinoma (RCC) occurring in around one-third of patients enrolled in clinical trials evaluating modern systemic therapies for this disease.Until recently, limited systemic therapeutic options TIE-DYE Hoodie were available for advanced RCC.Nowadays, a quiver of agents h

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The neuroprotective effect of melatonin in glutamate excitotoxicity of R28 cells and mouse retinal ganglion cells

Glaucoma is the leading cause of irreversible blindness.The progressive degeneration of retinal ganglion cells (RGCs) is the major characteristic Casters of glaucoma.Even though the control of intraocular pressure could delay the loss of RGCs, current clinical treatments cannot protect them directly.The overactivation of N-methyl-D-aspartic acid (N

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Caffeine, Postoperative Delirium And Change In Outcomes after Surgery (CAPACHINOS)-2: protocol for a randomised controlled trial

Introduction Delirium is a major public health issue for surgical patients and their families because it is associated with increased mortality, cognitive and functional decline, prolonged hospital admission and increased healthcare expenditures.Based on preliminary data, this trial tests the hypothesis that intravenous caffeine, given postoperativ

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Violence towards health care workers in a Public Health Care Facility in Italy: a repeated cross-sectional study

Abstract Background Violence at work is one of the major concerns in health care activities.The aim of this study was to identify the prevalence of physical and non-physical violence in a general health care facility in Italy and to assess the relationship between violence and psychosocial factors, thereby providing a basis for appropriate interven

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